For T0901317 experiments, mice were injected intraperitoneally with either vehicle (10%DMSO in 90% corn oil) or T0901317 (MedChem Express, HY-10626) at a dose of either 16.9 mg/kg or 50 mg/kg dose for either 4 days (1720) days post AAV-TBG-Cre treatment) or 14 days (720) days post AAV-TBG-Cre treatment)
Although there was no significant difference between groups, our study observed weight regain only in the subgroup of higher level of weight loss compared with the control group
Hospital Pharmacy , 48 (4), 282301
The pain signal has been turned down, but the tissue has not knitted back together yet
Other major players, which include AstraZeneca, Pfizer, Sanofi, Roche, Amgen, and Boehringer Ingelheim, are expanding pipelines via innovation, acquisitions, and partnerships
Since 2024, new launches, partnerships, and acquisitions such as PepsiCos acquisition of Poppi, One Bios USD 27 million fundraise, and Superguts expansion have focused on repositioning fiber and prebiotics for GLP-1 users and metabolically aware consumers