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Based on these findings, KEGG enrichment analysis further showed that irradiation mainly affected multiple signaling pathways related to inflammatory responses, apoptosis, and epithelial barrier damage, while EGCG-Zn treatment reversed these changes at the transcriptional level (Figs
The balance of the different CRP isoforms, monomeric (mCRP) or native pentameric (nCRP) within the plaque determines the preponderance of a proinflammatory or anti-inflammatory effect, respectively (165)
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