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Examples are MTHFR variants, which impact folate metabolism and homocysteine, FTO and MC4R, which are associated with weight regulation, CYP19A1, which is involved in aromatase and estrogen balance, ESR1 and ESR2, which are estrogen receptors, and variants in FSHR and LHCGR that alter ovarian response

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doi: 10.1016/S0140-6736(23)01200-X

Consulting health professionals for dosage advice is highly recommended

But the Phase 2 curve suggests total weight loss could reach 20 to 25% of body weight at peak effect for the highest dose group

Another potential mechanism suggested by experimental research is the potential GHK-Cu action on synthesis of matrix metalloproteinase-2 (MMP-2) and tissue inhibitors of metalloproteinases (TIMPs), which are deemed crucial for extracellular matrix remodeling