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Ibrahim et al., 2020)
In one study, participants using Tirzepatide experienced an average weight loss of 15% to 20% of their body weight, while those using Semaglutide saw reductions of around 10% to 15%
At the 3 month mark, the treatment group averaged between 6% and 8% reduction in body weight
The mechanism is thought to relate to glucagon-receptor activation and energy-substrate shifts, but it is not fully characterized
Furthermore, a study found that intraperitoneal injection of GLP-1 (Beinaglutide Injection) alleviates tissue injury effects in DSS-induced colitis mice by inhibiting intestinal inflammation, preserving the intestinal barrier, and modulating intestinal microbiota [219]
et al, 2023)
