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In this phase, the fasting schedule may remain at 16:8 or ease back to 14:10 as medication doses decrease and appetite naturally returns
Thats because GLP-1s are designed to slow gastric emptying, the process of the stomachs contents being released into the small intestine to aid digestion
For patients medically ineligible for surgery due to severe obesity or comorbidities, medication may be the only option
We always start Retatrutide alone for two to four weeks before adding MOTS-C
Whilst declining beta-cell function is thought to generally reduce the response to incretins, GLP-1 appeared to be the more important incretin hormone in T2D (Nauck et al, 2021)
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