This particular form represents the most reduced and chemically reactive state of cobalamin, rendering it highly receptive to binding a methyl group from a form of vitamin B9 called 5-methyltetrahydrofolate, the product of methylenetetrahydrofolate reductase (MTHFR), to generate methylcobalamin (MeCbl)
Two studies identified low levels of folate and significantly higher levels of the amino acid homocysteine in OCD patients compared with healthy controls
NSL literature pointer PMID 7764422 L-Carnitine laboratory index [PMID: 7764422] National Science Labs indexing note for PMID 7764422: review the PubMed methods, models, and limitations before citing
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