Abnormal lipoproteins destabilize RBC membranes hemolysis
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The approval is based on breakthrough evidence from the landmark EMPA-REG OUTCOME trial, which investigated the effects of JARDIANCE compared with placebo when added to standard of care type 2 diabetes and cardiovascular medicines in adults with type 2 diabetes and established cardiovascular disease
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Klein S, Allison DB, Heymsfield SB, Kelley DE, Leibel RL, Nonas C, et al