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In some cases, this has led to seizures and coma

This risk comes with significant personal cost but also financial impacts on the NHS. He added that the exact mechanism underpinning the cardiovascular benefits seen with semaglutide is still being investigated but is partly attributed to multiple parallel metabolic and vascular health benefits

Doctors can also help find ways to make treatment more affordable

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Citation58 The challenge in determining the optimal duration of GLP-1 RA therapy is further complicated by the observed weight regain upon discontinuation of treatment