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-synuclein in Parkinsons disease: causal or bystander
At least seventeen GLP-1RA clinical trials documented a delay in gastric emptying 25,26,27,28,29,30,31,32,33,34,35,36,37,38,39,40,41
There are two reasons that make these solutions non-viable
The results showed that mood improved and anxiety decreased at the 28mg/day dose.[ref] For patients with major depressive disorder, a study showed that the combination of curcumin (250mg) plus saffron (15mg/day) was effective in reducing depression scores, especially in people with atypical depression.[ref] In a comparison trial, saffron (30mg/day) was as effective as fluoxetine (Prozac) for mild to moderate depression after six weeks.[ref] Another study in adults with anxiety and depression looked at a 50mg saffron capsule taken twice a day
However, in the setting of alcohol consumption or malnourishment (or both) the amount needed to cause liver damage drops
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