The rationale for titrating upward over time, rather than starting at the target dose, mirrors the approach taken with other metabolic peptides: the goal is to identify the minimum effective dose for each individual while monitoring for tolerability
Nabekura T, Kamiyama S, Kitagawa S (2005) Effects of dietary chemopreventive phytochemicals on P-glycoprotein function
Notably, TPL reverses the silencing of pro-apoptotic genes through epigenetic reprogramming and weakens cellular stress defense mechanisms by suppressing HSP70 expression
doi:10.1590/1981-863720180003000083517 Ross K, VanNortwick M
If you have a B12 deficiency, thats likely the cause for your anemia in the first place
Glutathione participates in defined enzymatic conjugation and redox pathways