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Liraglutide does not alter behavioural markers of ALS in SOD1 G93A transgenic mice Due to the tolerated higher 75 nmol/kg liraglutide dose and the larger effect on blood glucose levels, we dosed SOD1 G93A transgenic mice with vehicle, 25 nmol/kg or 75 nmol/kg liraglutide from 25 to 90 days of age
The most harmful scenario is having gene variants that reduce glutathione levels and high toxin levels that deplete glutathione
Most meaningful BMI changes occur when treatment lasts at least 1216 weeks, with the most significant improvements seen over 612 months
Because the amino acid cysteine is a substrate for the rate-limiting step in the production of glutathione, it's important to make sure you're getting enough through diet and/or NAC supplementation
