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"Arginate" refers to the arginine salt form that wraps around those fifteen amino acids, shielding them from enzymatic breakdown, improving their solubility, and dramatically increasing how much of the peptide actually reaches systemic circulation when taken orally
Notably, this strategy is unsuitable for all patients, such as the elderly, malnourished, or those with folate-related complications (e.g., megaloblastic anemia or neurological issues), where prolonged deficiency poses risks [55,56,57]
Remember, B12 is needed for this cell to mature, so with insufficient B12 megaloblasts accumulate in your bone marrow and large red cells called macrocytes appear in your blood
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