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Diabetes Care 33:730732 Migoya EM, Bergeron R, Miller JL et al (2010) Dipeptidyl peptidase-4 inhibitors administered in combination with metformin result in an additive increase in the plasma concentration of active GLP-1

Methods A systematic review of the published literature was conducted in accordance with the Preferred Reporting Items for Systematic Reviews and Meta-analyses (PRISMA) guidelines

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PVN-cannulated Glp1r OBhM3Dq mice were PVN-infused with Bicuculline Methiodide (Sigma-Aldrich