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In other words, roughly two-thirds of every kilogram lost was fat, not muscle
It led to a 4% to 8% increase in risk compared with those with continuous use
Greater weight loss efficacy of tirzepatide 10 mg ( 3.2 kg) and 15 mg ( 5.2 kg) compared to semaglutide was also observed in an indirect comparison with data from the SUSTAIN FORTE study, where semaglutide was administered at the maximum hypoglycemic dose of 2.0 mg [49]
(Source: The World Data, April 2026) Tirzepatide Health Benefits Beyond Weight Loss Like semaglutide, the clinical evidence for tirzepatide extends well beyond weight loss
Plasminogen activator inhibitor-1 significantly decreased with liraglutide 3.0 mg versus placebo (Supplementary Table 8)
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