J Clin Invest 2010;120:1774-85
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Typical endpoints are clinical pregnancy rate, live birth rate, embryo quality as graded by morphology and time-lapse metrics and measures of sperm count, motility, and DNA fragmentation
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Di Meo, I., Colombelli, C., Srinivasan, B., de Villiers, M., Hamada, J., Jeong, S
Since metabolites are the final downstream products of transcription and translation, they are closest to the phenotype ( To date, to identify biomarkers for the diagnosis and treatment response of MDD, lipids ( By profiling the serum metabolites of the patients with MDD and the control group, metabolites showing differences between the groups were identified as potential biomarkers