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although benign, it can be socially bothersome

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This allows researchers to test a range of doses on a smaller cohort, identifying the minimum effective dose and any potential adverse effects before committing to a larger, more resource-intensive study

Concurrently, a reduction in the diversity of the intestinal microbiota was observed, characterized by a decrease in the relative abundance of Bacteroidetes and an increase in Proteobacteria

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However, the immune response of the CNS is complex and involves a myriad of diverse cell populations such as astrocytes, microglia, macrophages, NK cells, and T and B cells (Dringen and Arend, 2025)