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Then it is eliminated by liver metabolism and renal excretion [7]
A GLP-1R antagonist is thus predicted to reduce choroid plexus-mediated CSF secretion through a reduction in a PKA signalling pathway
There is no FDA-approved human trial
Patients need to adjust the dose reasonably under the guidance of a doctor to avoid discontinuing treatment due to side effects
Cardiometabolic risk means the likelihood of developing conditions such as heart disease, high blood pressure or type 2 diabetes
That is why side effects often peak during titration and settle down later
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