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Growth hormone-releasing peptides like sermorelin, promising, especially for specific groups, but more nuanced

Despite previous studies indicating that, compared to the Eli Lilly/Chugai series of small molecule agonists, Danuglipron (PF-06882961) has demonstrated better pharmacological properties that mimic GLP-1 peptides from in vitro activity testing to structural research

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They are choosing between a treatment available now (tirzepatide) and one that may become available in the next 12 to 18 months (CagriSema)