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While tirzepatide (Zepbound and Mounjaro) currently leads in terms of average weight loss in approved medications, CagriSema could become a strong competitor once Phase 3 results are released

In animals, reduced food intake and weight loss were closely linked to growth and bone development issues

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GLP-1 pills may be a good non-surgical option for some patients, but gastric sleeve surgery often produces more durable long-term weight loss, especially for patients with higher BMI levels or obesity-related health conditions

Zmuda-Trzebiatowska, E., Oknianska, A., Manganiello, V

PMC 7386876