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Figure S20
Glp-1 effects on islets: Hormonal, neuronal, or paracrine
Compounding does not alter the pharmacology of the active ingredient
Le Chatelier, E
The downstream effects include activation of hormone-sensitive lipase in adipose tissue (which breaks down stored triglycerides into free fatty acids), increased protein synthesis in skeletal muscle, enhanced cellular repair and turnover, elevated IGF-1 production from the liver, and improved lipid metabolism including reduced triglycerides
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