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Orforglipron showed stronger effects on blood sugar control, HDL cholesterol, and systolic blood pressure, while semaglutide showed larger effects on total body weight, waist circumference, and LDL cholesterol
Cant say enough
2026 Jan 7;392:e085304
Macroalbuminuria occurred less (2.2%) in exenatide group compared to placebo group (2.5%) [HR 0.87 (95% CI: 0.701.07)]
Dermatologists warn this may increase melanoma risk or make early skin cancers harder to detect
Any injection site reaction that persists beyond one week or progressively worsens should also prompt clinical evaluation to ensure appropriate management and rule out alternative diagnoses
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