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Most modern low-dead-space syringes minimize this to 2-5 microliters, which is negligible
[14] Cyanide poisoning [edit] In 2006 the FDA approved hydroxocobalamin for treating smoke inhalation, which can cause cyanide poisoning
These trials tracked numerous safety parameters and laboratory values, but vitamin b12 levels were not routinely monitored or reported in the published results
PMID 30074676
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Medical uses & FDA-recognized indications for B12 shots When discussing what B12 injections are for, it is helpful to distinguish between clinical medical necessity and general wellness support
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