While very high oral doses (1,000 to 2,000 mcg) can achieve some passive absorption without intrinsic factor roughly 1% of the dose is absorbed passively many clinicians prefer the reliability and rapid correction offered by injections in this population
Mice with loxP sites flanking the fifth TR exon (TR Floxed mice), developed by Shanghai Model Organism Center, Inc., were fertile and appeared indistinguishable from TR +/+ mice
Chawla A, Chawla R, Jaggi S
Donnelly KL, Smith CI, Schwarzenberg SJ, Jessurun J, Boldt MD, Parks EJ
Presented for research literature review only Uzuncakmak TK et al
The results showed that compared to a placebo, the combined reduction in the risk of kidney failure, worsening kidney function, and death due to kidney disease was 19%