Philipose, et al., 'Once-Monthly Maridebart Cafraglutide for the Treatment of Obesity - A Phase 2 Trial', N
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This mechanism contributes to glucose control through several physiological actions: Stimulating insulin release when blood glucose levels rise Reducing secretion of glucagon, a hormone that increases blood sugar Slowing gastric emptying, which helps control post-meal glucose spikes Promoting a feeling of fullness that may help reduce calorie intake Through these mechanisms, the medication helps patients achieve better metabolic balance and improved glycemic management
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However, compounded GLP-1 medications may not be FDA-approved, and the FDA has warned about adverse events in some compounded semaglutide cases