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doi: 10.1186/s12875-021-01369-0

Notably, the azo-containing chemotherapeutic drug procarbazine for the treatment of Hodgkins lymphoma and brain cancers was found to interact through a similar mechanism of action involving the transformation of GSH to GSSG and regeneration of the catalyst through a reaction with O 2 38,39 , providing feasibility of the proposed catalysis

Key Glutathione Facts: Glutathione is a protein thats naturally made in the liver

The first people who made these drugs, they didn't know if they were going to work, so obviously they took a big risk doing this, but there's much less risk now

Farooq et al., 2016