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It also modulates nitric oxide signaling, which regulates blood flow and inflammatory responses

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10.1126/science.abi8370 10 GongL.ChenK.ZhangH.ZhangS.XuR.LiuD.et al (2023)

It appears to: improve blood flow by improving the utilization of fatty acids for energy, which can help reduce muscle fatigue, increase oxygen supply to the affected limbs, and improve walking capacity reduce symptoms, such as leg pain (claudication), and improve the walking distance before the onset of pain

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The ER version is taken once a day and comes in 500 mg, 750 mg, and 1,000 mg doses