1 2 3 "Transcriptional Regulation by Nrf2"
It activates several overlapping pathways, notably VEGFR2 and nitric oxide synthesis via the Akt-eNOS axis, promoting angiogenesis, fibroblast activity, and neuromuscular stabilization
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CrossRef A Clinical Analysis of Brain Metastasis in Gynecologic Cancer: A Retrospective Multi-institute Analysis Young Zoon Kim, Jae Hyun Kwon, Soyi Lim Journal of Korean Medical Science.2015
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173 At the molecular level, gene modulation techniques, including siRNA- and shRNA-mediated silencing of efflux transporter genes (e.g., ABCB1, ABCG2), as well as CRISPR/Cas9-based gene editing, have successfully resensitized tumor cells to chemotherapy in preclinical models