Post hoc evaluations of the SUSTAIN 6 trial revealed that semaglutide markedly increased the incidence of diabetic retinopathy complications in individuals with a history of retinopathy, especially among insulin users, presumably due to the swift deterioration of pre-existing retinopathy following rapid glycemic control [91]
10.1016/j.cryobiol.2014.01.007 79
That said, both can be a healthy addition to a balanced diet and can be consumed with minimal risk of adverse effects on health.
Supplementing glycine and N-acetylcysteine (GlyNAC) in aging HIV patients improves oxidative stress, mitochondrial dysfunction, inflammation, endothelial dysfunction, insulin resistance, genotoxicity, strength, and cognition: Results of an open-label clinical trial
The injections should always be administered by a licensed professional, like a registered nurse or a skilled aesthetician, in a sterile setting
Second, additive effect risks where two compounds affecting the same system (like glucose metabolism) can stack their effects beyond safe levels