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Using a previously described approach 11,13,19 , we reconstructed the HG content for the key nodes in the tree and classified the HGs based on their mode of evolution: gene gains (novel, novel core and expanded) and gene reductions (contracted and lost)

doi: 10.1111/j.1600-065X.2007.00567.x 21 ObeidMTesniereAGhiringhelliFFimiaGMApetohLPerfettiniJLet al

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