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More recently, dual GIP/GLP-1 RAs, such as tirzepatide, as well as emerging dual and triple incretin-based therapies, have demonstrated substantial efficacy in both glycaemic and weight control
[4] Conditions that match a drugs FDA approval generally qualify, whether youre using these major GLP-1 brands or similar: Ozempic/Mounjaro: type 2 diabetes [5] Wegovy/Zepbound: obesity (BMI 30) [6] Wegovy/Zepbound: overweight with at least one weight-related condition (BMI 27 to under 30 plus hypertension, high cholesterol, sleep apnea, cardiovascular disease, or type 2 diabetes) [7] Zepbound: obstructive sleep apnea [8] Wegovy: metabolic-associated steatohepatitis (MASH) [9] Off-label conditions can count too when your clinician documents a real diagnosis such as prediabetes, binge eating disorder, or PCOS
R.CosentinoF.et al (2021)
Thats one way to understand the common phenomenon of yo-yo dieting, where weight cycles up and down like a roller coaster
Oct 2015;94(43):e1906
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