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doi: 10.1002/adma.202406140 339 LiPZhuLSongCWuMZhuXHeSet al
Similarly, tissue levels of inflammatory cytokines were significantly decreased
Transforming growth factor-1 (TGF-1) can induce the EMT phenotype in melanoma cells and upregulate the levels of GPX4 and SLC7A11, while gambogenic acid, a xanthone derived from traditional Chinese medicine Gamboge, can promote ferroptosis by inhibiting the SLC7A11/GPX4 pathway in melanoma cells stimulated by TGF-1
(2021) 33:241527.e6
The picture is complicated by the presence of additional MDHA- and DHA-reducing systems, in addition to the enzymes encoded by the genes shown in Table 1
Most available estimates come from theoretical analysis, anecdotal interpretation, or limited animal data
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