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Common adverse effects are predominantly gastrointestinal and typically emerge during dose escalation: Nausea (affecting 2050% of users initially) Vomiting and diarrhoea Constipation Abdominal pain and bloating Reduced appetite (therapeutic effect but may be excessive) Fatigue and headache Injection site reactions (redness, swelling or itching) These effects usually diminish over several weeks as the body adjusts

But doctors say obesity should be considered the same way as other chronic conditions that can be treated and kept under control through medication

"Comparative effectiveness of tirzepatide and semaglutide for obesity management in US clinical practice: a 6-month retrospective cohort study." J Endocrinol Invest

It also supports the detoxification process and promotes liver and immune health

Youll need to attach a new needle for each injection

The undiscounted retail price for some brand-name GLP-1 drugs can be more than $1,200 per month without insurance, though some manufacturers now offer self-pay plans at lower rates