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In human umbilical vein endothelial cells (HUVECs) and aortas from ApoE -/- mice, TMAO increased the concentrations of reactive oxygen species (ROS), especially superoxide, by inhibiting the SIRT3-SOD2-mitochondrial ROS signaling pathway (75)

doi: 10.1016/j.tifs.2024.104807 403 AmaliaNOrchardDFrancisKLKingE

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Fruits high in Vitamin C, such as oranges and strawberries

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DNA damage promotes mutations of suppressor in tumor such as calcium/calmodulin dependent serine protein kinase (CASK), p53, as well as stimulation of the epidermal growth factor receptor (EFGR) signaling pathway, which are important early events in gastric carcinogenesis (86, 87)