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The 2000 Drosophila lifespan paper provided one of the foundational findings (PMID 11087911), and Khavinson-laboratory rodent studies extended the lifespan observations into mouse and rat model systems through the 2000s
Bloodbrain barrier models have also used iPSCs, differentiated by Qian's method, derived from ALS patients with SOD4 or C9orf72 mutations
No source rates any of this above theoretical / in-vitro evidence
It also downregulated the double-strand breaks repair ability in colorectal cancer cells and enhanced the sensitivity of cancer cells to KU60648
Evidence and Safe Treatments Does BPC-157 cause erectile dysfunction
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