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Treating LN and proteinuria with RAAS blockade at maximum tolerated doses is recommended, complemented with a sodium-poor diet to optimize its effect ( The evidence on RAAS inhibition in recent immunosuppression-based trials shows that treatment in terms of nephroprotection is usually poorly optimized before induction therapy is initiated
We understand that this decision puts GLP-1 options out of reach for some members who seek the drugs for weight loss
These reports appear anecdotal rather than supported by robust clinical evidence
Hypertension, ischemic heart disease, patients with atherosclerosis and coronary artery disease, diabetes, chronic lung diseases, smoking and obesity are associated with low baseline GSH levels and reduced GSH/oxidized glutathione (GSSG) ratios (Khanfar and Al Qaroot, 2020
van der Zwaag, P
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