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Maintain consistent daily dose and site rotation records
Staff cited inadequate substance characterization, uncertain product quality, insufficient evidence of effectiveness for ulcerative colitis, sparse human safety data, and unresolved risks such as immunogenicity, aggregation, impurities, and long-term exposure
- Quality of weight loss (body composition): evidence suggests a greater reduction in fat mass, without a disproportionate increase in lean mass loss, in body-composition sub-studies
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severe abdominal pain, persistent vomiting, or an inability to pass gas requires urgent medical evaluation, since rare cases of bowel obstruction have been reported with GLP-1 receptor agonists
17 Combining pharmacotherapy with resistance training may help preserve lean body mass
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