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Some higher-dose trials reported weight loss averages up to 20%

The limited volume of distribution suggests that, like semaglutide, tirzepatide predominantly resides in the intravascular space, reflecting its extensive binding to plasma albumin

says Akhil Shenoy, MD, an endocrinologist at Aeroflow Diabetes in Arden, North Carolina

Colorectal cancer cells (HCT116 and MC38) were initially cultured in folate-deficient medium for 2 days, then transferred to media containing varying folate concentrations (20 nM and 200 nM) for 2 days, after which tumor supernatants and cells were harvested

Bottom Line Hair loss while taking semaglutide is real, but it's rarely a simple story

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