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In the previous study with similar overall design in white participants with T2D, the standard deviation of the within-participant differences was 0.162 for log(AUC 0 t ,SD,Icodec ) and 0.164 for log(dose-normalized AUC 0 t ,SD,Semaglutide ) [16]

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Dosing is individualized according to age, renalor hepaticfunction, concomitant medications, and presence of comorbid conditions such as glaucoma or urinaryretention, with careful monitoring for adverse effects such as drowsiness, drymouth, or QTprolongation in susceptible patients