GLP-1s: A Practical, Lower-Cost Path with Real Medical Support If youve looked into weight-loss medications lately, your feed is probably full of ads for injectable GLP-1s like Wegovy or Zepbound
Note also, that no studies to date have included patients with psoriatic arthritis and there is currently no evidence to suggest that GLP-1 agonists will be effective in treating normal-weight, non-diabetic patients with psoriasis
Proc Natl Acad Sci U S A (2019) 116(8):29963005
Fatigue is another commonly reported side effect of GLP-1 medications, particularly in the early stages of treatment
These include people with: Personal history of medullary thyroid carcinoma Family history of Multiple Endocrine Neoplasia syndrome type 2 History of severe pancreatitis Severe gastrointestinal disease Your doctor will review your medical history before prescribing any GLP-1 medication
Conversely, DKD in type 2 diabetes mellitus shows greater pathological heterogeneity, with some people developing classical glomerular lesions, while others present with atypical features such as prominent tubulointerstitial damage, vascular abnormalities, or coexisting non-DKD pathology [21,22]