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Could Ozempic and Other GLP-1 Drugs Treat Alcohol Use Disorder
doi:10.1056/NEJMoa2032183Wilding JPH, Batterham RL, Davies M, et al
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Mechanism involves NO system modulation (homeostatic regulationupregulating when deficient, moderating when excessive), VEGF/VEGFR2 upregulation for angiogenesis, FAK-paxillin pathway activation for cell migration (40% increase per Chang et al.), and EGR-1 transcription factor upregulation for growth factor sensitivity
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