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Example 15 coupling of the Semetreuptade side chain 6.0 g (10mmol) of Fmoc-AEEA-OH, 2.43 g (18mmol) of HOAt were weighed out, dissolved in DMF, 3.1ml of DIC (18mmol) were added in an ice-water bath at 0 to activate for 5 minutes, the peptide resin from example 11 was added, reacted for 2 hours, and then the Fmoc protecting group was removed with DBLK

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Real-world evidence in diabetes: relevance to clinical practice

Dose-Pause and Discontinuation Patterns Trial protocols paused dosing for protocol-defined adverse events

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2025;26:XX