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Am J Clin Nutr 2017

Months 4 to 6 and Beyond: Skin, Anti-Aging, and Long-Term Results The most visually striking sermorelin before and after changes often occur in the 4 to 6 month range, particularly for skin and anti-aging outcomes

doi: 10.1038/s12276-020-00500-y 265 CrocettoFFerroMBuonerbaCBardiLDolcePScafuriLet al

That said, oral supplementation is not without value when sustained over longer periods

L-carnitine prevents memory impairment induced by chronic REM-sleep deprivation [PMID: 28433816] Laboratory literature summary: L-carnitine prevents memory impairment induced by chronic REM-sleep deprivation

Ravesloot MJL, White D, Heinzer R, Oksenberg A, Pepin JL