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With each successive cycle, anthracycline metabolites accumulate in cardiac tissue, disrupting mitochondrial function, triggering apoptosis and ultimately causing irreversible loss of contractile muscle [54, 55]
Should we both be tested for this mutation
These effects help reduce oxidative stress and improve protein clearance capacity in affected neurons 64
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In these populations, IV or injectable B12 can swiftly correct deficiencies and reverse related complications such as peripheral neuropathy, cognitive decline, and megaloblastic anemia
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