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Moertel CG, Fleming TR, Creagan ET, Rubin J, O'Connell MJ, Ames MM: High dose vitamin C versus placebo in the treatment of patients with advanced cancer who have had no prior chemothrerapy : A randomized double blind comparison

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However, through several magnetic resonance spectroscopy studies (MRS) it has been shown that GSH levels are significantly decreased in the hippocampus, frontal, and cingulate cortices early in AD progression (Mandal et al., 2022)