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According to published research, it was developed in the 1990s and has been studied primarily in animal models and limited human trials
Vukajlovic, K
However, it is important to note that, until the FLOW trial, this benefit seemed mainly due to a reduced risk of persistently high level macroalbuminuria [34, 35]
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Obesity and overweight (2024) www.who.int/news-room/fact-sheets/detail/obesity-and-overweight GBD 2019 Risk Factor Collaborators (2020) Global burden of 87 risk factors in 204 countries and territories, 19902019: a systematic analysis for the global burden of disease study 2019, vol 396
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