Answer: Glucagon-like peptide-1 (GLP-1) receptor agonists, a class of medications that includes semaglutide (Wegovy, Ozempic, Rybelsus), tirzepatide (Zepbound, Mounjaro), liraglutide (Victoza, Saxenda), and orforglipron (Foundayo), have become increasingly popular for obesity treatment (Mehrtash, JAMA Intern Med 2025)
Its a surprisingly fragile molecule
doi: 10.1111/j.1600-0412.2011.01325.x 73 HaigG
B12 is crucial for red blood cell formation, neurological health, DNA synthesis, energy metabolism, and mood regulation
The effects can be experienced within the first few days, whether thats an effect on your appetite or side effects like nausea, vomiting or diarrhea. These two new drugs are part of a larger class of GLP-1 drugs that mimic the gut hormone GLP-1, which is made naturally in your intestines and brain
In cultures of LCs, rhGH directly activated steroidogenesis [12]