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Much remains to be clarified experimentally, but the hypothesis offers a biologically plausible and clinically suggestive framework for linking endogenous morphine, dopamine, GLP-1 therapeutics, and mitochondrial regulation in one evolutionary narrative

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Sitagliptin was granted FDA approval on 16 October 2006 (National Center for Biotechnology Information, 2023f)

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Fatima T, Mirza A, Fatima F, et al