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A comprehensive medical history is essential to identify contraindications, including personal or family history of medullary thyroid carcinoma or multiple endocrine neoplasia syndrome type 2, as GLP-1 agonists carry a boxed warning regarding thyroid C-cell tumors observed in rodent studies

This can make stools harder and drier, leading to constipation

Actual cost may vary based on your pharmacy, whether or not you qualify for discounts, or if you can participate in any savings programs

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Understanding the Shingrix vaccine uptake Shingrix is the recommended vaccine to help prevent shingles in adults age 50 and older, but understanding how well adult vaccination recommendations translate into real-world practice can be challenging

To date, Phase 3 clinical trial data have also shown significant weight-loss outcomes, including up to 28.7% average body weight loss at 68 weeks in one obesity trial and 16.8% average weight loss at 40 weeks in adults with type 2 diabetes, with additional Phase 3 readouts still expected throughout 2026