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Weight loss itself lowers hypertension risk, but tirzepatide also has direct cardiovascular effects: it improves insulin sensitivity, reduces inflammatory markers, and activates GIP receptors that influence vascular tone
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Ipamorelin produces lower peak GH concentrations but maintains pituitary axis integrity
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Conclusion# CagriSema and retatrutide each represent a compelling approach to next-generation obesity treatment
Kahl A, Stepanova A, Konrad C, Anderson C, Manfredi G, Zhou P, et al
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