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For these assays, increased levels of cAMP were measured as an increase of the 485/535 nm FRET ratio serving as a readout for binding of cAMP to the H188 biosensor that is based on the exchange protein activated by cAMP (Chepurny, Bonaccorso et al

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However, as competition in the GLP-1 RAs market becomes more intense, relying solely on effectiveness is no longer enough for products to stand out